Samsung KNOX separates data and apps into containers, making it difficult for malware or intruders to gain access or cause damage where they aren't wanted, and it is integrated to a device's hardware and each individual level of the Android framework, making it a full-coverage solution. The software has been available to enterprises for some time now, alleviating concerns that Android isn't secure enough to protect corporate data and communications.
The push for BYOD (bring your own device) policies in workplaces has been on the rise for the last couple of years, but many corporations have frowned upon Android devices due to "security issues" within the OS. Samsung is looking to change that mindset with its newly-announced KNOX solution.
Essentially, KNOX is a security-enhanced version of Android – based on the NSA-approved SE Linux – optimized for Samsung's SAFE (Samsung for Enterprise) program.