As we know, the source code for Android 4.0 "Ice Cream Sandwich" is going to be published fairly soon, which means developers of all trades will be able to download, modify, and compile it into ROMs. A few great examples of this are handset manufacturers (SE, Motorola, HTC, etc) working on incorporating ICS into new and existing devices as well as CyanogenMod developers merging the source with all the awesome modifications they've added into CM so far.
If you're like most Android users, you may run into slight space issues when it comes to available internal storage for apps. The daunting task you face, then, is to go through each of your apps and locate the major megabyte offenders. What a pain.
Alternatively, you may discover that your precious SD card is suddenly refusing to write a new episode of the Stuff You Should Know podcast (which is awesome), so now you have to drop everything to figure out where the fat is.