I first played Cipher Prime's Splice when it was part of a recent fourth Humble Bundle, and it still enjoys a place in my Installed Games list on Steam. It's a puzzle game that involves taking different strains of bacteria and "splicing" them, moving around cells in order to fit an provided outline. Of course, you have a set amount of moves, and added "mutation" cells will change the game in different ways: for instance, one mutation will cause each cell attached to it to grow, or split identically.